Among the 24 severe COVID-19 patients, only 16 cases were selected because of their complete electronic medical records, subsequently, the abnormal laboratory results of multiple organs, such as kidney (creatinine and urea), liver (alanine aminotransferase and aspartate aminotransferase), and heart (High sensitivity troponin T and creatine kinase-MB), were further analyzed. Here, MB is linked to COVID-19.