(E) Overlap between genomic alterations in MARCH5 and PTEN. (F) Gene alterations for MARCH5, MCL1, PMAIP (NOXA), HUWE1 (MULE), and BCL2L11 (BIM) in TCGA dataset and MSKCC/DFCI PCa datasets. Here, MARCHF5 is linked to posterior cortical atrophy.