In line with that research, the tumor volume and tumor weight in the JMJD2B shRNA group were significantly decreased compared with those of the control shRNA group (P < 0.05) (Figure 6 A-D), and these decreases were blocked in the group stably overexpressing LC3B established using a lentivirus targeting the LC3B gene (Figure 6A-D). Here, MAP1LC3B is linked to neoplasm.