METTL3 and hepatocellular carcinoma: Moreover, patients were further divided into four groups: Mettl3-high/Snail-high, Mettl3-low/Snail-low, Mettl3-low/Snail-high, and Mettl3-high/Snail-low, which further illustrated that HCC individuals with Mettl3-high/Snail-high expression tended to have the worst overall survival rates than any other groups (Figure 6D).