Therefore, the aim of the present study was to analyse a larger case series of lymphoma entities, some with an established link to EBV (BL, DLBCL, HL, and follicular lymphoma—FL [20, 21]) and some not (T-lymphoblastic lymphomas (T-LL), hairy cell leukemias (HCL) and mantle cell lymphomas (MCL) by using quantitative PCR and droplets digital PCR (ddPCR) measurement of EBV genes and micro-RNAs in purified neoplastic cells along with highly sensitive RNAscope ISH assay for EBNA1 mRNA, in addition to routine techniques such as immunohistochemistry for LMP1 and EBER-ISH on whole-tissue sections. This evidence concerns the gene PDLIM7 and mantle cell lymphoma.