While IHC for LMP1 and EBER-ISH identified a proportion of EBV-positive tumors overlapping that reported in the literature in BL, DLBCL, FL, and HL, measurement of viral gene load, as well as of viral microRNA and mRNA expression, identified traces of EBV exposure also in occasional tumor cells of samples negative by conventional tools. This evidence concerns the gene PDLIM7 and Burkitt lymphoma.