Similarly, two to three variants each (rs2349075, rs529458487, rs398206, rs408825, rs4383, rs4384, and rs6001033) from three other loci (2q33-q34, 21q22.3, and 22q13.1) also overlapped with melanocyte eQTLs, where lower CASP8, higher MX2, and higher MAFF levels were correlated with melanoma risk, respectively (Supplementary Table 7). This evidence concerns the gene CASP8 and melanoma.