We also evidenced dysregulation of several genes involved in the non-suppressive_T cell_versus_activated_T reg signaling pathway (Figure 3A), with a reduced expression of ALX1, GFRA1, CXCL16, GPC4, GSTM4, and INHBE and overexpression of BDNF and DOK5 in the MM BM-MSC compared with HD BM-MSC (Figure 3A,B). The gene discussed is CXCL16; the disease is Miyoshi myopathy.