NFKB1 and MALT lymphoma: In contrast, other frequent genetic defects, such as the t(1;14)(p22;q32), t(14;18)(q32;q21), and t(11;18)(q21;q21) translocations, which are detected in over 25% of gastric and over 50% of lung MALT lymphomas, result in overexpression of BCL10 or MALT1 and constitutive activation of the canonical NF-κB pathway [161].