APC and colorectal carcinoma: With the aim to identify molecular mechanisms through which the two pathways could reinforce each other, in this study, we investigated the role of hypoxia-induced non-coding RNAs (lncH19 and miR-675-5p) on two different CRC cell lines: the SW620 and the HCT116, that display, respectively, mutation in APC and β-catenin [5,23,24].