In Asian patients, the modified PAGE-B, which includes the serum albumin level in addition to the PAGE-B variables, showed better predictive performance than PAGE-B and four other scores: REACH-B (variables: male sex, age, alanine aminotransferase, HBeAg status, and HBV-DNA), GAG-HCC (variables: age, male sex, HBV-DNA, HBV core promoter mutations, cirrhosis), CU-HCC (variables: age, albumin, bilirubin, HBV-DNA, cirrhosis), and PAGE-B [37,38]. The gene discussed is ALB; the disease is Cirrhosis.