IGKV2D-24 and incontinentia pigmenti: Furthermore, it was shown that stimulation of nAChRs with nicotine is associated with decreased neutrophils migration by inhibition of adhesion molecule expression both on the endothelial surface and neutrophils, whereas deficiency of α7 leads to a faster recruitment of neutrophils and decreased bacterial burden after i.p. infection with Escherichia coli [45,46].