A few more clinical trials have also reported improvements in individual cardiometabolic indices, such as insulin, lipidemic profile indices (TC, LDLC, HDLC and TG), GGT and blood pressure in patients with OSA after lifestyle-induced weight loss [12,13,14], but no study to date has examined the effect of lifestyle modifications on the presence of the MS. Here, INS is linked to obstructive sleep apnea syndrome.