Altogether 888 children diagnosed with ALL were identified from 2010 to 2016, and these patients were associated with positive TEL-AML1 fusion gene, hyperdiploidy, hypodiploidy, IL3-IGH rearranged, positive E2A PBX1 fusion gene, positive BCR-ABL1 fusion gene, or MLL rearranged. This evidence concerns the gene KMT2A and acute lymphoblastic leukemia.