TARDBP and neurodegenerative disease: Mixed pathology is common with these diseases, and TDP-43 pathology can be found not only alongside Lewy bodies (Nakashima-Yasuda et al., 2007), amyloid-β plaques, and tau tangles (Amador-Ortiz et al., 2007) in cases of neurodegenerative disease but also in clinically normal aged individuals (Wennberg et al., 2019).