The expression of MPC1 was significantly upregulated in the cholesterogenic group in KIRC, LGG, lung adenocarcinoma (LUAD) and LUSC, and the expression of MPC2 was significantly upregulated in the cholesterogenic group in PAAD, sarcoma (SARC) and CESC (Figure 5B), similar to our findings in HCC. The gene discussed is MPC1; the disease is hepatocellular carcinoma.