Interestingly, both the glomerular cell number positive for HuR staining and the cellular staining intensity of HuR were enhanced in diseased glomeruli with IgA nephropathy from mild to diffuse marked mesangial proliferation and the staining levels of glomerular HuR quantified by Image-J were markedly increased in IgA nephropathy with increased glomerular grading and sclerosis (Figure 7C). Here, ELAVL1 is linked to IgA glomerulonephritis.