Figure 3B-D shows the graphical representations of the mean ± SD of each glomerular staining score for each group. Glomerular PAS, FN, and Col-IV staining scores increased by 268%, 184%, and 139% respectively in disease control rats as a result of nephritis, compared with normal control rats. KH-3 treatment decreased the matrix score significantly, which are shown by the decreases in disease-induced ECM accumulation of 59% for PAS (Figure 3B), 49% for FN (Figure 3C), and 64% for Col-IV (Figure 3D). Here, FN1 is linked to nephritis.