The EMT can be induced by several of numerous pleiotropic growth factors or cytokines (EGF, HGF, FGF, TGF-β, NOTCH, IL-6, IL-8, among others) (Thiery et al., 2009; Kim et al., 2016) that can be produced by different cells present in the tumor. Here, CXCL8 is linked to neoplasm.