Simple linear regression analysis showed that the factors that significantly affected the lumbar spine BMD were sex, presence of hypertension, presence of diabetes mellitus, BMI, triglyceride level, grip strength, and SMI; the factors that significantly affected the femoral neck BMD were sex, HD duration, serum creatinine level, tartrate-resistant acid phosphatase 5b level, undercarboxylated osteocalcin (ucOC) level, total N-terminal propeptide of type I procollagen level, grip strength, and SMI. Here, COL1A2 is linked to diabetes mellitus.