For instance, miR-323-3p suppressed the expression of transmembrane protein with EGF-like and 2 follistatin domain (TMEFF2) and the activation of AKT and ERK pathways, by which it inhibited the apoptosis in non-small-cell lung cancer (NSCLC) cell lines (43). The gene discussed is AKT1; the disease is non-small cell lung carcinoma.