The inhibitory effect of MSCs on mast cell degranulation was also confirmed in BALB/c mice with AD induced by dinitrochlorobenzene (DNCB) and treated with hAD-MSCs and in BALB/c mice with AD induced by OVA and treated with SOD3-MSCs (Kim D. S. et al., 2018; Sah et al., 2018). The gene discussed is SOD3; the disease is Alzheimer disease.