Immunofluorescence shows co-dominance of both IgG and C3 and occasionally IgM (e.g., hepatitis C related MPGN) or a “full house” pattern (including IgG, IgM, IgA, C1q, C3, C4 and kappa and lambda light chains) as seen in SLE. This evidence concerns the gene C3 and systemic lupus erythematosus.