This includes mTOR, atypical PKC (aPKC)-RhoGDI, Rab11 family interacting protein 1 (Rab11-FIP1), and phosphatidylinositol-4-phosphate 5-kinase (PIP5K) signaling which can lead to fibrosis formation or tumor cell invasion and migration (42, 64–67). The gene discussed is MTOR; the disease is neoplasm.