CSF2 and congenital rubella syndrome: Several biomarkers have been correlated with CRS and/or NTX development, such as LDH, ferritin, CRP, inflammatory cytokines, GM-CSF, von Willebrand Factor, and angiopoietin 2 (reflecting endothelia activation) and lower platelet count, but a definitive predictive model is still lacking (22, 67, 76, 79–82).