According to Condeelis and Pollard, other processes that lead to cancer progression are angiogenesis (VEGF, ADM, PDGF, MMPs, TGF-β, CCLa, SEMA3A), intravasation, and extravasation (EGF, CCL-18, P2Y2 receptor), migration and invasion (MMPs, serine proteases, cathepsins, MIP-1β, EGF) (11, 12). This evidence concerns the gene EGF and cancer.