The top impacted pathways in monocytes were as following: cytokine-cytokine receptor interaction (FDR = 6 × 10−6), transcriptional misregulation in cancer (FDR = 1 × 10−4), Type I DM (FDR = 2.6 × 10−3), cell adhesion (FDR = 0.003), cytoskeleton (FDR = 2.0 × 10−3), RAS signaling (FDR = 2.0 × 10−3), and JAK-STAT pathway (FDR = 2.0 × 10−3) (Figure 4A). The gene discussed is SOAT1; the disease is cancer.