These analyses suggested that only CCAAT/enhancer-binding protein β (C/EBPβ) was predicted both to bind within the −92 to −130 bp of TDO2 enhancer essential region and to display a strong positive correlation with the expression of TDO2 (Figure 1E, Spearman: 0.47) and CYP1B1 (Figure 1F, Spearman: 0.56, Figure 1G) in TCGA GBM microarray data. The gene discussed is TDO2; the disease is glioblastoma.