Similar to TDO2 and CEBPB, IL1B was enriched in the mesenchymal subtype of GBM patients in the TCGA dataset (Figure 3A), and as expected, the expression of IL1B positively correlated with TDO2 as well as CYP1B1 in GBM (Figure 3B). Here, CYP1B1 is linked to glioblastoma.