DMD and Duchenne muscular dystrophy: These studies are consistent in showing that the absence of dystrophin leads to altered myogenesis and myofiber commitment in skeletal muscle, originally observed in X Chromosome-Linked Muscular Dystrophy (mdx, genetic mouse model of DMD that completely lacks full-length dystrophin) mouse embryos (Merrick et al., 2009) and skeletal muscle biopsies from human fetuses affected by DMD (Farini et al., 2016).