UCHL1 and neoplasm: We previously reported that ubiquitin C-terminal hydrolase L1 (UCHL1), a member of DUBs, is associated with favorable prognosis in neuroblastoma (Gu et al., 2018a) and is critical for the survival and immunosuppressive function of tumor-associated immune cells (Gu et al., 2018b), suggesting that these DUBs are closely related with tumor development and progression.