KCNH2 and familial long QT syndrome: It was also under extensive investigation (Naksuk et al., 2019) and published that LQTS is a type of arrhythmias, in which “torsades de pointes” arrhythmia causes ventricular tachycardia, VF, and sudden death by the mutation of various genes (KCNQ1/E1 and KCNH2/hERG) underlying potassium repolarization currents, including IKr and IKs (Anson et al., 2004; Nerbonne and Kass, 2005; Daubert et al., 2007; Vink et al., 2018; Zhou et al., 2019).