SIRT1 and Hepatic steatosis: Resveratrol can be considered as a pharmacological SIRT1 activator (Zhang et al., 2015) and take effects on hepatic steatosis by improving lipid-related gene transcriptional expression, oxidative stress and inflammation (Cheng et al., 2019), meanwhile decreasing ER stress (Ding et al., 2017) via the autophagy (Liu et al., 2015a).