MAPK8 and Hepatitis: Jianpi Huoxue formula (mainly consists of Atractylodis macrocephalae Rhizoma, Salvia miltiorrhizae Radix Et Rhizoma, Paeonia Radix Alba, Alismatis Rhizoma, and Schisandrae Chinensis Fructus) may have beneficial effects on MCD induced liver inflammation and apoptosis via the inhibition of the JNK phosphorylation and the activation of caspase 3 and 7 proteins (Feng et al., 2019).