NR1H4 and metabolic dysfunction-associated steatotic liver disease: Several lines of evidences have suggested the importance of FXR in the management of NAFLD (Yang et al., 2010; Lefebvre and Staels, 2014; Lu et al., 2014; Xiong et al., 2014; Carr and Reid, 2015; Jin et al., 2015; Tully et al., 2017; Xiao et al., 2017).