Finally, since WDFY1 could serve as a biomarker in Alzheimer’s disease (AD), we evaluated WDFY1 protein levels in the hippocampus of AD patients (see Table 2 for sample information) with (AD+) or without (AD-) psychosis compared to controls (Figure 2I). The gene discussed is WDFY1; the disease is early-onset autosomal dominant Alzheimer disease.