Liver damage induced by PCM (Group 2) caused significant (p < 0.05) increased in serum liver marker enzymes (i.e., ALT, AST and ALP), and TB levels when compared to the normal control group (Group 1), which suggested that there was leakages of the said enzymes and TB into the blood circulation resulting from the liver damaged. Here, GPT is linked to paracoccidioidomycosis.