CRP and schizophrenia: Two studies have however found evidence that higher CRP is protective against schizophrenia, mirroring our finding regarding self-harm (Hartwig et al., 2017, Prins et al., 2016): these authors have hypothesised that this may reflect increased susceptibility to early-life infection, although it may also be influenced by socioeconomic or lifestyle characteristics (Hartwig et al., 2017).