To further investigate the mechanism through which CD200/CD200R signaling regulates synaptic plasticity after stroke, we assessed the expression of p-p65, phospho-c-Jun N-terminal kinase (p-JNK), phospho-extracellular signal-regulated kinase-1/2 (p-ERK1/2), and phospho-protein 38 (p-p38) MAPKs in the ipsilateral sensorimotor cortex. Here, CD200R1 is linked to stroke disorder.