SYP and Stroke: Data from Western blotting demonstrated that the protein level of PSD-95 was increased significantly at 4, 7, and 28 days (group main effect, F4, 30 = 101.1, P < 0.0001), and SYP levels were increased at 28 days (group main effect, F4, 30 = 23.64, P < 0.0001) after CD200Fc i.c.v injection post-stroke (Fig. 5a–c).