Four additional AD risk SNPs were nominally associated with obesity (rs17125944 at FERMT2, pBMI = 4.03 × 10–5, pBMI corr = 2.50 × 10–3; rs3851179 at PICALM; pBMI = 0.002, rs2075650 at TOMM40/APOE, pBMI = 0.024, rs3865444 at CD33, pBMI = 0.024) (Hinney et al., 2014). This evidence concerns the gene PICALM and Alzheimer disease.