TOMM40 and Alzheimer disease: Alleles A of CD33 rs3865444 and A of TOMM40 rs157580 were both protective factors for AD onset (OR = 0.94, 95% CI: 0.90–0.98, p‐value = .003; OR = 0.62, 95% CI: 0.57–0.66, p‐value < .001) (Bao, Wang, & Mao, 2016).