Along with 36 cancer-gene associations (FDR < 0.05, Wald test) found in the European ancestry, we identified two specific cancer-gene associations in the African ancestry: BRCA2 in ovarian cancer (OV) (OR = 8.5 [95% CI, 1.5–47.4]; FDR = 0.045) and LUSC (OR = 41.4 [95% CI, 6.1–275.6]; FDR = 0.002). This evidence concerns the gene BRCA2 and cancer.