Since TLR polymorphisms have been associated with changes in susceptibility to many diseases, including cancers [47] and TLRs promote the survival of cancer cells [48], we also correlated the coexistence of previously genotyped TLR (TLR2, TLR4 and TLR9) polymorphisms [18] with the VDR polymorphisms. This evidence concerns the gene TLR2 and cancer.