CSF3 and COVID-19: Also, patients with severe COVID-19 in intensive care units have shown elevated plasma levels of several cytokines (IL-2, IL-7, IL-10, TNF-α), MCP1, granulocyte-colony stimulating factor (GCSF), IFN-γ-induced protein 10 (IP-10), and macrophage inflammatory proteins (MIP-1A), suggesting a cytokine storm, resulting in hyper-inflammation and excessive reactions, such as hyperpyrexia and organ failure associated with disease severity, which can be life-threatening [53].