AKT1 and acute lymphoblastic leukemia: It is thus possible that CIGB-300, CK2, and the IL-7/IL-7R receptor complex could “prematurely meet” at the cell surface during the first steps of peptide internalization, thus accounting for the observed downstream inhibition of JAK/STAT and PI3K/Akt signaling pathways, once T-ALL cells are in the presence of IL-7.