Fig. 1). These results confirm previous reports on gene fusion events in multiple NSCLC and acute leukemia cell lines that were used for our analysis [7, 8, 35]. Interestingly, Fcirc identified ∼10 different f-circRNA transcripts for the PML-RARα fusion gene in NB4 leukemia cells (depending on the computational assumptions), which warrants further investigation and biological characterization (Suppl. Table 12). The gene discussed is PML; the disease is acute leukemia.