PFKP and breast carcinoma: PFK has three types of isoforms and among them PFKP is known as the phosphofructokinase's platelet-specific isoform, which plays vital roles in various types of cancer, including breast cancer [12], glioblastoma [13], renal clear cell carcinoma [14], pancreatic cancer [15], and oral squamous cell carcinoma [16] through metabolic reprogramming.