These neutrophil chemotactic factors activate polymorphonuclear neutrophils, which contribute to the pathogenesis and progression of atherosclerosis [62]), 2p12 (associated in women, candidate gene ABCC1, coding for an ATP-binding cassette, which are involved in cholesterol homeostasis and vascular inflammation [63], and 18q12.3 (associated in men, candidate gene PSTPIP2, which has been detected as differentially expressed gene in the atherosclerosis [64]). This evidence concerns the gene PSTPIP2 and atherosclerosis.