Abnormal cerebral gyration or cerebellar atrophy in Galloway–Mowat syndrome (GAMOS) [17–19]; cerebral and cerebellar atrophy and stroke-like lesions in CoQ10 nephropathies [20–22]; ventriculomegaly in patients with CRB2-glomerulopathy [23] and subcortical changes in patients with SGPL1 biallelic pathogenic variants [24] have been described. The gene discussed is SGPL1; the disease is Cerebellar atrophy.