SHANK1 and nervous system disorder: Analysis of GO Biological process enriched terms using Enrichr revealed that a significant number of differentially spliced genes were involved in axonogenesis, protein localisation to synapse and dendritic morphogenesis, including genes critical for neuronal homoeostasis and implicated in neurological diseases, e.g., Shank1, Bdnf, Map2, Dlg4, Nrxn1, Nrxn2 and Ncam1 (Fig. 7c).