INS and type 2 diabetes mellitus: This study showed that magnesium plus zinc supplements in subjects with CHD and T2DM during 12 weeks caused a significant decrease in FPG and insulin levels, and significant increase in HDL-cholesterol, but it had no effect on the HOMA-IR, QUICKI, total cholesterol, triglycerides, VLDL-cholesterol and LDL-cholesterol levels.