Upon necropsy, lungs from animals injected with A375-GLO1_WT displayed pronounced metastatic pathology, largely absent from tissue obtained from A375-GLO1_KO-injected mice, and tumor multiplicity was attenuated as a result of GLO1 genetic deletion [3 ± 1 versus 18 ± 4 (tumors per lung; p < 0.001); (Figure 5B,C)]. The gene discussed is GLO1; the disease is neoplasm.