PPARA and Parkinson disease: Cinnamic acid, another component present in green propolis, showed neuroprotective effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of PD, detected by the attenuation of the nigrostriatal cell loss via activation of peroxisome proliferator-activated receptor alpha, which is involved in regulation of energy homeostasis and is known to have anti-inflammatory and antioxidative stress properties [79].