ANGPT1 and rheumatoid arthritis: Evening primrose oil and its principal phytocompound, gamma linolenic acid, were shown to influence chronic inflammatory processes as in rheumatoid arthritis by reducing the expression of proinflammatory and angiogenic cytokines—vascular endothelial growth factor (VEGF) and angiopoietin-1 (ANG-1), and enhanced the anti-inflammatory and anti-angiogenic activities of aspirin and celecoxib [5,66].