In fact, within one week following peroral C. jejuni challenge, secondary abiotic IL-10−/− mice suffer from wasting and bloody diarrhea during this acute and non-self-limiting course of enterocolitis which is due to C. jejuni LOS induced and TLR4 dependent immune responses within intestinal, extra-intestinal, and even systemic tissue sites [16,17]. Here, IL10 is linked to enterocolitis.